50 Results for "

AS-2

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "AS-2" in MCE Product Catalog:

1
L-Lactate-13C sodium (20% in water)
L-Lactate-13C sodium (20% in water)
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1 Cited Publications
Cat. No.: HY-Y0479AS2
CAS No.: 201595-69-9
Synonyms: (S)-2-Hydroxypropanoic acid-13C sodium
L-Lactate- 13C ((S)-2-Hydroxypropanoic acid- 13C) sodium is the 13C-labeled L-Lactic acid sodium (HY-W040233). L-lactate Sodium is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid Sodium has antiproliferative activity [2] .
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L-Arginine-d7 hydrochloride
L-Arginine-d7 hydrochloride
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Cat. No.: HY-N0455AS2
CAS No.: 204244-77-9
Synonyms: (S)-(+)-Arginine-d7 hydrochloride
L-Arginine-d7 (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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Uridine 5'-diphosphate-13C9,15N2 dilithium
Uridine 5'-diphosphate-13C9,15N2 dilithium
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Cat. No.: HY-113359AS2
Purity:  99.5%
Synonyms: UDP-13C9,15N2 dilithium
Uridine 5'-diphosphate- 13C9, 15N2 (UDP- 13C9, 15N2) dilithium is the 13C9, 15N2-labeled Uridine 5'-diphosphate (HY-113359). Uridine-5'-diphosphate is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis [2].
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Moxifloxacin-d3 hydrochloride
Moxifloxacin-d3 hydrochloride
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Cat. No.: HY-66011AS2
CAS No.: 2734919-98-1
Synonyms: BAY 12-8039-d3
Moxifloxacin-d3 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin hydrochloride is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [2] .
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Simvastatin acid-d3 ammonium
Simvastatin acid-d3 ammonium
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Cat. No.: HY-119695AS2
Synonyms: TenivAStatin-d3 ammonium
Simvastatin acid-d3 (Tenivastatin-d3) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A) .
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Difloxacin-d3
Difloxacin-d3
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Cat. No.: HY-121272AS2
CAS No.: 1173147-93-7
Purity:  ≥98.0%
Synonyms: A-56619-d3
Difloxacin-d3 is the deuterium labeled Difloxacin .
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Raltegravir-d4 potassium
Raltegravir-d4 potassium
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Cat. No.: HY-10353AS2
Synonyms: MK 0518-d4 potASsium
Raltegravir-d4 (potassium) (MK 0518-d4 (potassium)) is deuterium labeled Raltegravir (potassium). Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection.
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Risdiplam-hydroxylate-d6
Risdiplam-hydroxylate-d6
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Cat. No.: HY-109101AS2
Risdiplam-hydroxylate-d6 is a Risdiplam-hydroxylate tritium substitute. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels .
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Taurolithocholic acid-d4-1 sodium
Taurolithocholic acid-d4-1 sodium
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Cat. No.: HY-113308AS2
Taurolithocholic acid-d4-1 (sodium) is the deuterium labeled Taurolithocholic acid. Taurolithocholic acid sodium is an orally active bile acid and antiviral agent. Taurolithocholic acid sodium upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid sodium also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid sodium serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid sodium shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid sodium not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis [2] .
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Nicardipine-d4 hydrochloride
Nicardipine-d4 hydrochloride
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Cat. No.: HY-12515AS2
Synonyms: YC-93-d4
Nicardipine-d4 hydrochloride is deuterated labeled Nicardipine hydrochloride (HY-12515A). Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure .
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5-Hydroxy Propafenone-d6 hydrochloride
5-Hydroxy Propafenone-d6 hydrochloride
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Cat. No.: HY-12773AS2
Synonyms: GPV-129-d6 hydrochloride
5-Hydroxy Propafenone-d6 hydrochloride is deuterated labeled 5-Hydroxy Propafenone.
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Sacubitril-d5 hemicalcium
Sacubitril-d5 hemicalcium
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Cat. No.: HY-15407AS2
Synonyms: AHU-377-d5 hemicalcium
Sacubitril-d5 (AHU-377-d5) hemicalcium is deuterium-labeled Sacubitril hemicalcium (HY-15407A) .
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Etifoxine-d5
Etifoxine-d5
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Cat. No.: HY-16579AS2
CAS No.: 1346598-10-4
Etifoxine-d5 is the deuterium labeled Etifoxine. Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents [2] .
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(1S)-Calcitriol-d6
(1S)-Calcitriol-d6
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Cat. No.: HY-10002AS2
CAS No.: 1202355-83-6
Synonyms: 1α,25-Dihydroxy-3-epi-vitamin D3-d6
(1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion .
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Valproic acid-d4-1 sodium
Valproic acid-d4-1 sodium
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Cat. No.: HY-10585AS2
Synonyms: Sodium Valproate-d4-1; VPA-d4-1 sodium; 2-Propylpentanoic acid-d4-1 sodium
Valproic acid-d4-1 sodium is the deuterium labeled Valproic acid sodium.
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Baloxavir-d1
Baloxavir-d1
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Cat. No.: HY-109025AS2
CAS No.: 2246959-09-9
Synonyms: Baloxavir acid-d1; S-033447-d1
Baloxavir-d1 is the deuterium labeled Baloxavir (HY-109025A). Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [2].
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Tamoxifen-d2
Tamoxifen-d2
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Cat. No.: HY-13757AS2
CAS No.: 3047060-10-3
Synonyms: ICI 47699-d2; (Z)-Tamoxifen-d2; trans-Tamoxifen-d2
Tamoxifen-d2 (ICI 47699-d2) is the deuterium labeled Tamoxifen (HY-13757A). Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen can also be dissolved in corn oil (HY-Y1888) for use in inducing gene knockout in CreER transgenic mice. Tamoxifen has better solubility in corn oil compared to Tamoxifen Citrate (HY-13757).
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Degarelix-d7 TFA-1
Degarelix-d7 TFA-1
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Cat. No.: HY-16168AS2
Synonyms: FE 200486-d7 TFA-1
Degarelix-d7 TFA-1 (FE 200486-d7 TFA-1) is the deuterium labeled Degarelix TFA. Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer [2].
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Alogliptin-13C,d3 benzoate
Alogliptin-13C,d3 benzoate
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Cat. No.: HY-A0023AS2
Synonyms: SYR-322-13C,d3 benzoate
Alogliptin- 13C,d3 (SYR-322- 13C,d3) benzoate is deuterium labeled Alogliptin Benzoate (HY-A0023). Alogliptin Benzoate (SYR-322) is a potent, selective and orally active inhibitor of DPP-4 with an IC50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin Benzoate can be used for the research of type 2 diabetes.
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Cinnamic acid-13C3
Cinnamic acid-13C3
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Cat. No.: HY-N0610AS2
CAS No.: 2734410-01-4
Synonyms: 3-Phenylacrylic acid-13C3; β-Phenylacrylic acid-13C3
Cinnamic acid- 13C3 (3-Phenylacrylic acid- 13C3) is the 13C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells [2].
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