4 Results for "

ASIC-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "ASIC-IN-1" in MCE Product Catalog:

Cat. No.: HY-147391
CAS No.: 308088-10-0
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

ASIC-IN-1 is a potent acid sensing ion channel inhibitor with an IC50 value of < 10 µM. ASIC-IN-1 causes a dose- dependent reduction of the pain intensity [1].
loading...
    loading...
Cat. No.: HY-131879
CAS No.: 309711-59-9
Purity:  99.83%
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits [1].
loading...
    loading...
Cat. No.: HY-P1249
CAS No.: 230960-31-3
Research Areas:  

Neurological Disease

Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) .
loading...
    loading...
Cat. No.: HY-P1249A
Research Areas:  

Neurological Disease

Neuropeptide SF (mouse,rat) TFA is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF TFA increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) .
loading...
    loading...