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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
ATG101
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "ATG101" in MCE Product Catalog:
Cat. No.: HY-P990778
CAS No.: 2756879-35-1
Synonyms: ATG-101
Target:
Research Areas:
Cat. No.: HY-RS01139
Target:
Research Areas:
ATG101 Human Pre-designed siRNA Set A contains three designed siRNAs for ATG101 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176451
CDK9 degrader-1 (Compound AZ-9) is a selective CDK9 degrader (DC50: 0.4073 µM). CDK9 degrader-1 recruits ATG101 to initiate the autophagy-lysosome pathway and forms autophagosomes by recruiting LC3, which then fuses with lysosomes to degrade CDK9 and its partner protein Cyclin T1 (DC50: 1.215 µM). CDK9 degrader-1 induces caspase 3-mediated apoptosis. CDK9 degrader-1 has antitumor activity in a mouse HCT116 xenograft model .
Cat. No.: HY-P703352
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C12orf44
Species:
Source:
Cat. No.: HY-181815
CAS No.: 1884222-37-0
SBP-5147 is an orally active ULK1/ULK2 inhibitor, with an IC50 of 2 nM against ULK1 and an IC50 of 53 nM against ULK2. SBP-5147 inhibits the phosphorylation of Beclin-1 and Vps34, reduces autophagy flux, downregulates the expression of ATG13 and ATG101, upregulates the expression of MHC-I, induces caspase-dependent apoptosis, and decreases the viability of non-small cell lung cancer cells. SBP-5147 is applicable to research related to non-small cell lung cancer [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
