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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
AZD2281
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "AZD2281" in MCE Product Catalog:
375
375 Cited Publications
Synonyms: AZD2281; KU0059436
Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator. Olaparib cannot cross the intact blood-brain barrier (BBB) .
1
1 Cited Publications
Cat. No.: HY-10162R
CAS No.: 763113-22-0
Synonyms: AZD2281 (Standard); KU0059436 (Standard)
Target:
Research Areas:
Olaparib (Standard) is the analytical standard of Olaparib. This product is intended for research and analytical applications. Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator .
Synonyms: AZD2281-d5; KU0059436-d5
Cat. No.: HY-10162S1
Purity: 99.57%
Synonyms: AZD2281-d8; KU0059436-d8
Synonyms: AZD2281-d4-1; KU0059436-d4-1
Cat. No.: HY-163817
CAS No.: 3032451-58-1
PARP1/2-IN-3 (Compound 29) is an orally active inhibitor for PARP 1 and PARP 2 with IC50 of 0.2235 nM and <0.001 nM. PARP1/2-IN-3 inhibits the proliferation of Capan-1 wildtype, AZD2281 or BMN673 resistant cells with IC50 of 1.82-9.98 nM. PARP1/2-IN-3 exhibits antitumor efficacy in mice .
Cat. No.: HY-10162S4
Synonyms: AZD2281-d4-2; KU0059436-d4-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
