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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Amidoxime
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Amidoxime" in MCE Product Catalog:
13
13 Publications Verification
Cat. No.: HY-P1005
CAS No.: 201608-14-2
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5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
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2
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Upamostat (WX-671), a prodrug of WX-UK1, is an orally active serine protease inhibitor. Upamostat inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer .
Cat. No.: HY-W031471A
CAS No.: 51285-05-3
Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide with antimicrobial activity. Pyrazine-2-amidoxime shows killing and inhibiting properties against Candida albicans, fungal pathogen and Gram-positive bacteria .
Synonyms: N'-hydroxy-4-phenylbenzene-1-carboximidamide
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Biphenyl-4-amidoxime (N'-hydroxy-4-phenylbenzene-1-carboximidamide) is a synthetic intermediate useful for pharmaceutical synthesis.
Cat. No.: HY-W023757
CAS No.: 1594-57-6
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N-Hydroxyisonicotinamidine is an amidoxime-based collector. N-Hydroxyisonicotinamidine can be used in the synthesis of substituted α-1,2,4-oxadiazolo esters .
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Thiophene-2-amidoxime is a synthetic intermediate useful for pharmaceutical synthesis.
Cat. No.: HY-W590911
CAS No.: 95649-37-9
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Indole-3-amidoxime is a synthetic intermediate useful for pharmaceutical synthesis.
Cat. No.: HY-W055845
CAS No.: 19227-13-5
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4-Methylbenzamide oxime is a model of benzamide oxime and can be used as a substrate for mitochondrial amidoxime reducing component (mARC) catalytic enzyme reduction .
Cat. No.: HY-178104
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HDAC-IN-93 is a HDAC inhibitor with promising total pan-HDAC inhibitory activity. HDAC-IN-93 demonstrates significant broad-spectrum antiproliferative activity across various cancer cell lines. HDAC-IN-93 induces cell apoptosis along with necrosis. HDAC-IN-93 can be used for the studies of prostate cancer and breast cancer .
Cat. No.: HY-119844
CAS No.: 34297-34-2
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Anidoxime is an Amidoxime derivative, and an orally active analgesic agent. Anidoxime can be used for the research of post-surgical pain .
Cat. No.: HY-W749521
CAS No.: 1449029-77-9
Synonyms: Azilsartan Amidoxime
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Azilsartan impurity 20 (Azilsartan amidoxime) is an impurity of Azilsartan.
Cat. No.: HY-119844A
CAS No.: 31729-11-0
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Anidoxime hydrochloride is an Amidoxime derivative, and an orally active analgesic agent. Anidoxime hydrochloride can be used for the research of post-surgical pain .
Cat. No.: HY-174454
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Antitrypanosomal agent 24 is a benzothiazole amidoxime with strong and selective antitrypanosomal activity (IC50 = 0.92 μM). Antitrypanosomal agent 24 is a substrate of the P-glycoprotein efflux pump. Antitrypanosomal agent 24 has high membrane permeability and good metabolic stability. Antitrypanosomal agent 24 binds to DNA/RNA by intercalation .
Cat. No.: HY-16512
CAS No.: 798560-68-6
Synonyms: WX-671 hydrogen sulfate
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Upamostat (WX-671) hydrogen sulfate, a prodrug of WX-UK1 (HY-100415), is an orally active serine protease inhibitor. Upamostat hydrogen sulfate inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat hydrogen sulfate can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer .
Cat. No.: HY-130235
CAS No.: 58033-22-0
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Naprodoxime hydrochloride is a derivative of Piracetam (HY-B0585). Naprodoxime hydrochloride acts as a potent antidepressant and anti-aggressive agent .
Cat. No.: HY-187200
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SP-393D is an amidoxime-based prodrug inhibitor targeting dengue virus NS2B/NS3. The EC50 values of SP-393D in Huh7 cells infected with DENV-1, DENV-2, DENV-3 and DENV-4 are 1.41, 0.066, 0.66 and 0.071 μM, respectively, while its CC50 against Huh7 cells is >100 μM. SP-393D exhibits pan-serotypic activity against dengue virus serotypes 1, 2, 3 and 4. SP-393D binds to the allosteric pocket of dengue virus NS2B/NS3 protease and generates additional hydrogen bonding interactions. SP-393D can be used in studies related to dengue virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
