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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Argonaute+2
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Argonaute+2" in MCE Product Catalog:
1
1 Cited Publications
BCI-137 is a Argonaute 2 (AGO2) inhibitor. By inhibiting AGO2 function, reducing PTPN6/SHP-1 protein levels and enhancing STAT1 phosphorylation, BCI-137 restores the sensitivity of tumor cells to IFN-γ. BCI-137 effectively enhances the recruitment, activation and cytotoxicity of CD8 + T cells. BCI-137 exerts a synergistic effect with anti-PD-1 antibodies and significantly reduces tumor volume in preclinical mouse models. BCI-137 exhibits favorable safety profiles and does not cause significant weight loss or death in mice. BCI-137 can be used in research related to bladder cancer, colorectal cancer, melanoma and other related fields .
Cat. No.: HY-P80441
Synonyms: EIF2C2, AGO2, Protein argonaute-2, Argonaute2, hAgo2, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2, PAZ Piwi domain protein, Protein slicer, eIF-2C 2, eIF2C 2, PPD
Cat. No.: HY-P74423Y
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AGO2; HAGO2; Prev. EIF2C2; Eukaryotic Translation Initiation Factor 2C 2; Prev. CASC7; Long Intergenic Non-Protein Coding RNA 980; LINC00980; Argonaute 2, RISC Catalytic Component; Q10; Argonaute 2; Cancer Susceptibility Candidate 7 (Non-Protein Coding);
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Cat. No.: HY-P74423
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: AGO2; HAGO2; Prev. EIF2C2; Eukaryotic Translation Initiation Factor 2C 2; Prev. CASC7; Long Intergenic Non-Protein Coding RNA 980; LINC00980; Argonaute 2, RISC Catalytic Component; Q10; Argonaute 2; Cancer Susceptibility Candidate 7 (Non-Protein Coding);
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Cat. No.: HY-P72835
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AGO2; HAGO2; Prev. EIF2C2; Eukaryotic Translation Initiation Factor 2C 2; Prev. CASC7; Long Intergenic Non-Protein Coding RNA 980; LINC00980; Argonaute 2, RISC Catalytic Component; Q10; Argonaute 2; Cancer Susceptibility Candidate 7 (Non-Protein Coding);
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
