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Results for "

Benzomalvin A

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118463
    Benzomalvin A

    		Neurokinin Receptor Neurological Disease
    Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with Ki values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .
    <em>Benzomalvin</em> <em>A</em>
  • HY-114673
    Benzomalvin B

    		Neurokinin Receptor Others
    Benzomalvin B is the less active analogs of Benzomalvin A. Benzomalvin B is weakly active against substance P .
    <em>Benzomalvin</em> B
  • HY-116620
    Benzomalvin C

    		Others Infection
    Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/mL in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC50 value of 130 μM for recombinant IDO. It is isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E.
    <em>Benzomalvin</em> C

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