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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
C27
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "C27" in MCE Product Catalog:
Cat. No.: HY-P3418
CAS No.: 891861-48-6
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Cat. No.: HY-108043
CAS No.: 875647-81-7
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AZD-2327 is a potent and selective δ-opioid receptor agonist. AZD-2327 binds to the human opioid receptor (Ki of 0.49 and 0.75 nM and EC50 of 24 and 9.2 nM at the C27 and F27 isoforms, respectively). AZD-2327 shows selectivity of >1000-fold over the human μ- and κ-opioid receptor subtypes as well as >130 other receptors and channels. AZD-2327 exhibits antidepressant and anxiolytic activities and can be used for the research of neurological disease .
Cat. No.: HY-P3418A
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Cat. No.: HY-CE01242
Synonyms: C27:0-coenzyme A
Target:
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C27:0-CoA (C27:0-coenzyme A) is a coenzyme A derivative .
Cat. No.: HY-161748
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PD-1/PD-L1-IN-46 (compound (R)-C27 ) is an PD-1/PD-L1 antagonist with IC50 value of 18.66 nM .
Cat. No.: HY-123357
CAS No.: 1456807-80-9
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IMM-H004, a coumarin derivative, possesses neuroprotective and potent free radical scavenging abilities. IMM-H004 significantly inhibits amyloid-β (Aβ)-induced cytotoxicity and apoptosis, offering potential value for research into neurodegenerative diseases such as Alzheimer's disease. Additionally, IMM-H004 is also capable of effectively blocking the calcium mobilization and chemotaxis induced by CKLF1-C27 (HY-P3418), thereby alleviating asthmatic pathological changes in the lung tissue of CKLF1 transgenic mice .
Cat. No.: HY-E71711
Target:
Research Areas:
3α,7α,12α-Trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase (EC 1.17.99.3) is an oxidoreductase primarily involved in the shortening of the C27 bile acid side chain during bile acid biosynthesis.
Cat. No.: HY-W414824
CAS No.: 1246298-66-7
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3β,7β-Dihydroxy-5-cholestenoic acid is a C27 acid that displays elevated levels in Niemann-Pick type C and Niemann-Pick type B diseases, contributing to toxicity in oculomotor neurons. It is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1.
Cat. No.: HY-117313S2
Cat. No.: HY-P700456
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SCDO1; DLL3; delta like canonical Notch ligand 3; Drosophila Delta homolog 3 ; Delta3
Cat. No.: HY-P82418
Synonyms: CYP27A1; CYP27; Sterol 26-hydroxylase; mitochondrial; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; Cytochrome P-450C27/25; Cytochrome P450 27; Sterol 27-hydroxylase; Vitamin D(3) 25-hydroxylase
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
