1 Result for "

CBDD

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CBDD" in MCE Product Catalog:

Cat. No.: HY-179432
CAS No.: 2699950-81-5
Synonyms: CBDD
Cannabitwinol is a selective thermosensitive TRP modulator and NF-κB inhibitor. Cannabitwinol inhibits TNFα-induced NF-κB-driven transcription and TNFα-induced IL-8 release, and exhibits anti-inflammatory and antioxidant activities. Cannabitwinol shows selectivity for cold-activated TRP channels, activating TRPA1 (EC50 = 3.0 μM) and antagonizing TRPM8 (IC50 = 3.9 μM), but has no significant affinity for heat-activated TRP channels such as TRPV1 and TRPV2. Cannabitwinol can be used in research related to inflammatory skin diseases, cold allodynia, and hyperalgesia .
loading...
    loading...