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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
CBM
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "CBM" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases .
Cat. No.: HY-W250721A
CAS No.: 9007-20-9
Synonyms: CBM 940
Cat. No.: HY-W250721
CAS No.: 9007-20-9
Synonyms: CBM 980
Cat. No.: HY-W250721B
CAS No.: 9007-20-9
Synonyms: CBM 934
Cat. No.: HY-W250721C
CAS No.: 9007-20-9
Synonyms: CBM 941
Cat. No.: HY-W250721J
CAS No.: 9007-20-9
Synonyms: CBM 960
Cat. No.: HY-173097
CAS No.: 2086298-33-9
Synonyms: VH032-Boc derivative 1
(S,R,S)-AHPC-Boc derivative 1 (Compound 80-9; VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1, leading to ubiquitination and subsequent proteasomal degradation of MALT1. (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-κB signaling pathway by disrupting the CBM complex, demonstrating potential for inducing apoptosis in ABC-DLBCL cells. (S,R,S)-AHPC-Boc derivative 1 is promising for research of MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL) .
Cat. No.: HY-121914
CAS No.: 66774-02-5
Synonyms: o-Chlorotriphenylmethanol
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Research Areas:
(2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca 2+ channel blocker .
Cat. No.: HY-W250721H
CAS No.: 9007-20-9
Synonyms: CBM 970
Cat. No.: HY-W250721K
CAS No.: 9007-20-9
Synonyms: CBM 996
Cat. No.: HY-W250721L
CAS No.: 9007-20-9
Synonyms: CBM 676
Cat. No.: HY-179305
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Research Areas:
CBM-4077 is a PROTAC E3 ligand that can be used for synthesis of PROTACs, such as BCL6-760 (HY-178777). BCL6-760 is a potent BCL6 PROTAC degrader with anti-tumor activity .
Cat. No.: HY-W044285
CAS No.: 324017-22-3
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Research Areas:
Cat. No.: HY-W250721I
CAS No.: 9007-20-9
Synonyms: CBM 990
Cat. No.: HY-136967
CAS No.: 81968-16-3
Synonyms: CBM36-733
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Mergocriptine (CBM36-733) is a dopamine receptor agonist and SARS-CoV-2 M pro ligand. Mergocriptine regulates ambulatory activity .
Cat. No.: HY-121914R
CAS No.: 66774-02-5
Synonyms: o-Chlorotriphenylmethanol (Standard)
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Research Areas:
(2-Chlorophenyl)diphenylmethanol (Standard) is the analytical standard of (2-Chlorophenyl)diphenylmethanol. This product is intended for research and analytical applications. (2-Chlorophenyl)diphenylmethanol (UCL 1880) is an analog of the metabolite 2-chlorophen-diphenyl-methanol (CBM) of 2-chlorophenyl, The IC50 for sI(AHP) inhibition is 1-2 μM. (2-chlorophenyl)diphenylmethanol is a weak Ca2+ channel blocker .
Cat. No.: HY-106796
CAS No.: 146452-37-1
Synonyms: CBM 11
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Research Areas:
(-)-(S)-Bromofosfamide (CBM 11) is an anti-cancer agent and a bromine-substituted IFO analog. (-)-(S)-Bromofosfamide can be studied in research on non-small cell lung cancer .
Cat. No.: HY-W419324
CAS No.: 324017-23-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
