146452-37-1
146452-37-1
Chemical Structure
(-)-(S)-Bromofosfamide
Synonym(s): CBM 11
- CAS No.: 146452-37-1
- Formula:C7H15BrClN2O2P
- Molecular Weight:305.54
IUPAC Name: (S)-3-(2-bromoethyl)-2-((2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide
InChIKey: CQEQYBJQFPXKPE-AWEZNQCLSA-N
SMILES: ClCCN[P@@]1(OCCCN1CCBr)=O
Biological Activity: (-)-(S)-Bromofosfamide (CBM 11) is an anti-cancer agent and a bromine-substituted IFO analog. (-)-(S)-Bromofosfamide can be studied in research on non-small cell lung cancer[1][2].
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(-)-(S)-Bromofosfamide | (-)-(S)-Bromofosfamide (CBM 11) is an anti-cancer agent and a bromine-substituted IFO analog. (-)-(S)-Bromofosfamide can be studied in research on non-small cell lung cancer. | |||||||||||||||||||||
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References
- [1]. Kobylińska, K., et al., (2001). Pharmacokinetics and toxicity of oral (-)-(S)-bromofosfamide in lung cancer patients. Arzneimittel-Forschung, 51(7), 600-603. [Content Brief]
- [2]. Liang, J., et al., (2007). Design of new oxazaphosphorine anticancer drugs. Current pharmaceutical design, 13(9), 963-978. [Content Brief]
Keywords
