2 Results for "

CP 122721

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CP 122721" in MCE Product Catalog:

Cat. No.: HY-10049
CAS No.: 145742-28-5
CP 122721 is an orally active NK1 receptor antagonist. CP 122721 attenuates cisplatin-induced vomiting in ferrets (ID50: 0.08 mg/kg). CP 122721 inhibits kainate (KA)-induced seizure activity and CA1 neuronal cell death in rats. CP 122721 is useful in the study of depression, asthma, and irritable bowel syndrome (IBS) .
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Cat. No.: HY-10049A
CAS No.: 145877-52-7
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

CP 122721 hydrochloride is a potent, non-peptide and selective nonpeptide neurokinin NK1 antagonist, with a pIC50 of 9.8 for human NK1 receptor expressed in IM-9 cells. CP 122721 hydrochloride exhibits anxiolytic and antidepressant-like effects .
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