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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
CUL4A
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "CUL4A" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4's core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 μM, respectively .
Cat. No.: HY-RS03362
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CUL4A Human Pre-designed siRNA Set A contains three designed siRNAs for CUL4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28983
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Cul4a Rat Pre-designed siRNA Set A contains three designed siRNAs for Cul4a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22460
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Research Areas:
Cul4a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cul4a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703246
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CULlin-4A; CUL4A; Homo sapiens; Human
Species:
Source:
Cat. No.: HY-P86842
Synonyms: 2810470J21Rik antibody; AW495282 antibody; CUL 4A antibody; CUL-4A antibody; CUL4A antibody; CUL4A protein antibody; CUL4A_HUMAN antibody; CULlin-4A antibody; MGC36573 antibody; MGC64071 antibody;
Cat. No.: HY-181164
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Research Areas:
PROTAC BRD4 Degrader-43 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-43 recruits the DCAF1-DDB1-Cul4A E3 ligase complex via a Vpr-derived peptide moiety to induce BRD4 ubiquitination and degradation through the ubiquitin-proteasome system. PROTAC BRD4 Degrader-43 exhibits potent HIV latency-reversing activity. PROTAC BRD4 Degrader-43 can be used for the research of HIV-1 latent infection . (Pink: BRD4 ligand (HY-13030); Blue: Cul4A-DDB1-DCAF1 ligand (HY-P11640); Black: conjugate of PEG linker + cell-penetrating peptide (HY-P2483))
Cat. No.: HY-P11640
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Cat. No.: HY-P702817
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cereblon-DDB1-CUL4A-Rbx1 Complex
Cat. No.: HY-P702826
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cereblon-DDB1-CUL4A-Rbx1 Complex
Species:
Source:
Cat. No.: HY-P703559
Purity: ≥ 95%, as determined by reducing SDS-PAGE
Synonyms: C4orf30
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Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
