2813310-07-3

KH-4-43 Chemical Structure
2813310-07-3

Chemical Structure

KH-4-43

  • CAS 番号: 2813310-07-3
  • Formula:C19H10ClF3N2O4
  • Molecular Weight:422.74

IUPAC Name: 3-(1-(4-chlorophenyl)-1H-pyrazol-4-yl)-7,8-dihydroxy-2-(trifluoromethyl)-4H-chromen-4-one

InChIKey: KDPAGFLLKCODNF-UHFFFAOYSA-N

SMILES: O=C1C2=CC=C(C(O)=C2OC(C(F)(F)F)=C1C3=CN(C4=CC=C(C=C4)Cl)N=C3)O

Biological Activity: KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4's core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 μM, respectively[1].

製品番号 製品名 純度 製品説明 Pricing
HY-148602 		KH-4-43 99.72% KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4's core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 μM, respectively.
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This product is a controlled substance and not for sale in your territory.

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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