9 Results for "

CXXC5

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "CXXC5" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-131447
CAS No.: 2226664-93-1
Purity:  ≥98.0%
Synonyms: A3051
Target:  

GSK-3 Wnt β-catenin

Research Areas:  

Metabolic Disease

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases .
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Cat. No.: HY-124156A
CAS No.: 2989396-34-9
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Metabolic Disease

KY-02327 acetate, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl)-CXXC5 interaction inhibitor. KY-02327 acetate shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation .
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Cat. No.: HY-P11112
CAS No.: 1609454-11-6
Target:  

β-catenin Wnt Collagen

Research Areas:  

Inflammation/Immunology

PTD-DBM is a CXXC5-Dvl protein-protein interaction inhibitor and also a Wnt/β-catenin pathway activator. PTD-DBM interferes with the Dvl-binding function of CXXC5, disrupts the negative feedback regulation of the Wnt/β-catenin pathway, induces β-catenin expression and nuclear translocation, and increases the production of type I collagen, α-smooth muscle actin and endothelin-1. PTD-DBM is applicable to studies related to androgenetic alopecia and skin wound healing .
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Cat. No.: HY-RS03415
Research Areas:  

Others

CXXC5 Human Pre-designed siRNA Set A contains three designed siRNAs for CXXC5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-178227
CAS No.: 2319609-67-9
KY19334 is a CXXC5-DVL inhibitor. KY19334 can activate the Wnt/β-catenin pathway by inhibiting CXXC5-Dvl interaction. KY19334 can inhibit cancer cells proliferation, migration, invasion and transformation by inhibiting CDK1. KY19334 can accelerate wound healing and exert regenerative effects. KY19334 can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as cutaneous squamous cell carcinoma and diabetes .
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Cat. No.: HY-124156
CAS No.: 2093407-25-9
Target:  

Wnt

Research Areas:  

Metabolic Disease

KY-02327, a metabolically stabilized KY-02061 analog, is a potent Dishevelled (Dvl)-CXXC5 interaction inhibitor. KY-02327 shows an activating effect on the Wnt/β-catenin pathway, resulting in promotion of osteoblast differentiation .
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Cat. No.: HY-RS18171
Research Areas:  

Others

Cxxc5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxxc5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24645
Research Areas:  

Others

Cxxc5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxxc5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-131448
CAS No.: 854171-31-6
Purity:  99.64%
Target:  

β-catenin Wnt

Research Areas:  

Metabolic Disease

A3051 is a potent and orally active inhibtor of CXXC5-DVL extracted from patent WO2020079569, has an IC50 of 63.06 nM. A3334 can be used for the research of high fat diet (HFD)-induced and methionine-choline deficient diet (MCD)-induced phenotypes such as obesity, diabetes, and NASH .
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