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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CYP1A2 substrates
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CYP1A2 substrates" in MCE Product Catalog:
8
Target:
Research Areas:
Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
Category:
Other Monoterpenes Terpenoids Other Diseases Plants Umbelliferae Vernonia Schreb. Disease Research Fields
Target:
Cat. No.: HY-W015998
CAS No.: 5543-58-8
Cat. No.: HY-W267897
CAS No.: 220001-53-6
Synonyms: 7-BFC
Target:
Research Areas:
7-Benzyloxy-4-(trifluoromethyl) coumarin (7-BFC) is a coumarin-based fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl) coumarin serves as a substrate for cDNA-expressed CYP1A2 and CYP3A4, and is metabolized into 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl) coumarin supports metabolic studies of cytochrome P450 subtypes via its fluorescent metabolite .
Cat. No.: HY-W015998S
CAS No.: 773005-79-1
Cat. No.: HY-116780A
CAS No.: 1225-65-6
Target:
Research Areas:
Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent. Prothipendyl hydrochloride is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19 and CYP3A4. Prothipendyl hydrochloride has sedating and psychomotorically damping effects. Prothipendyl hydrochloride can be used for psychomotoric agitation, sleep disorder and anxiety research .
Cat. No.: HY-W015697
CAS No.: 612-58-8
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
3-Methylquinoline is a selective cytochrome P450 (CYP1A2) inhibitor with an IC50 of 13 μM. 3-Methylquinoline can reduce the metabolic clearance of CYP1A2 substrate drugs. 3-Methylquinoline can inhibit the activation of carcinogenic precursors .
Cat. No.: HY-124158
CAS No.: 220853-65-6
Target:
Research Areas:
KR-60436 is a reversible H +/K +-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates .
Target:
Research Areas:
Prothipendyl is a tricyclic azaphenothiazine neuroleptic agent. Prothipendyl is a substrate of the CYP isozymes CYP1A2, CYP2D6, CYP2C19 and CYP3A4. Prothipendyl has sedating and psychomotorically damping effects. Prothipendyl can be used for psychomotoric agitation, sleep disorder and anxiety research .
Cat. No.: HY-111338R
CAS No.: 321-64-2
Research Areas:
Tacrine (Standard) is the analytical standard of Tacrine. This product is intended for research and analytical applications. Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
