773005-79-1
Chemical Structure
(R)-(+)-Warfarin-d5
- CAS No.: 773005-79-1
- Formula:C19H11D5O4
- Molecular Weight:313.36
IUPAC Name: ethyl-2,2,2-d3 (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
InChIKey: PJVWKTKQMONHTI-VLGPFOJQSA-N
SMILES: CC(C[C@H](C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C2=C(C3=CC=CC=C3OC2=O)O)=O
Biological Activity: (R)-(+)-Warfarin-d5 is the deuterated-labeled (R)-(+)-Warfarin (HY-W015998). (R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity. (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases[1][2].
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(R)-(+)-Warfarin-d5 | 99.23% | (R)-(+)-Warfarin-d5 is the deuterated-labeled (R)-(+)-Warfarin (HY-W015998). (R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity. (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases. | ||||||||||||||||||||
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(R)-(+)-Warfarin | 99.55% | (R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity. (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases. | ||||||||||||||||||||
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Keywords
