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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
CYP3A7
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "CYP3A7" in MCE Product Catalog:
Cat. No.: HY-18642
CAS No.: 1390637-82-7
Synonyms: PF-4981517
Target:
Research Areas:
CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism .
Cat. No.: HY-113482
CAS No.: 80434-32-8
Synonyms: 1β-OH-DCA
Target:
Synonyms: 16α-Hydroxy-DHEA; 16α-OH-DHEA; 16α-hydroxy DHEA
Target:
Research Areas:
16a-Hydroxydehydroisoandrosterone (16α-Hydroxy-DHEA) is a metabolite of the endogenous steroid hormone dehydroepiandrosterone. 16α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosterone via 16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol.
Synonyms: Desmethylsildenafil; UK-103,320
Target:
Research Areas:
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .
Cat. No.: HY-Z8033
CAS No.: 130606-60-9
Target:
Research Areas:
N-Desmethyl diltiazem hydrochloride is a substrate for CYP3A7 metabolism, which is the predominant fetal form and is minimally expressed in adults .
Cat. No.: HY-RS03474
Target:
Research Areas:
CYP3A7 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP3A7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-117605R
CAS No.: 139755-82-1
Synonyms: Desmethylsildenafil (Standard); UK-103,320 (Standard)
Research Areas:
N-Desmethyl Sildenafil (Standard) is the analytical standard of N-Desmethyl Sildenafil. This product is intended for research and analytical applications. N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .
Cat. No.: HY-W740175
CAS No.: 3869-32-7
Target:
Research Areas:
6b-Hydroxy triamcinolone acetonide is a metabolite of the synthetic corticosteroid Triamcinolone acetonide (HY-B0636). 6b-Hydroxy triamcinolone acetonide is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
