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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CYP51A1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CYP51A1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N7266
CAS No.: 16910-32-0
Category:
Infection Human Gut Microbiota Metabolites Natural Products Sorghum bicolor (Linn.) Moench Gramineae Plants Endogenous metabolite Disease Research Fields
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Cat. No.: HY-RS03486
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CYP51A1 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP51A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W714655
CAS No.: 112893-26-2
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Becliconazole is a fungal CYP51A1 inhibitor. Becliconazole can be used in research on fungal infections .
Cat. No.: HY-149617
CAS No.: 3032391-34-4
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CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target (CYP51/PD-L1) inhibitor, with IC50 values of 0.17 and 0.021 μM, respectively. CYP51/PD-L1-IN-4 exhibits excellent antifungal and antidrug-resistant fungal activity in vitro. CYP51/PD-L1-IN-4 can be used for fungal infections research .
Cat. No.: HY-144643
CAS No.: 2502095-64-7
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CYP51/HDAC-IN-1 is a potent, orally active CYP51/HDAC dual inhibitor. CYP51/HDAC-IN-1 inhibits important virulence factors and down-regulated resistance-associated genes. CYP51/HDAC-IN-1 exhibits potent therapeutic effects for both tropical candidiasis and cryptococcal meningitis .
Cat. No.: HY-116568R
CAS No.: 178928-70-6
Synonyms: JAU-6476 (Standard)
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Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor .
Cat. No.: HY-156149
CAS No.: 3032386-49-2
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CYP51/PD-L1-IN-1 (compound L11) is a quinazoline compound with antifungal activity. CYP51/PD-L1-IN-1 is a dual inhibitor of CYP51 (IC50: 0.884 μM) and PD-L1 (IC50: 0.083 μM), which can induce early apoptosis of fungal cells in the cell cycle. CYP51/PD-L1-IN-1 also significantly reduced intracellular IL-2, NLRP3, and NF-κBp65 protein levels, induced mitochondrial damage and ROS accumulation, and ultimately led to fungal lysis and death .
Cat. No.: HY-156150
CAS No.: 3032386-58-3
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CYP51/PD-L1-IN-2 (compound L20) is a quinazoline compound with antifungal activity. CYP51/PD-L1-IN-2 is a dual inhibitor of CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.017 μM), which can induce early apoptosis of fungal cells in the cell cycle. CYP51/PD-L1-IN-2 also significantly reduced intracellular IL-2, NLRP3, and NF-κBp65 protein levels, induced mitochondrial damage and ROS accumulation, and ultimately led to fungal lysis and death .
Cat. No.: HY-156151
CAS No.: 3032386-59-4
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CYP51/PD-L1-IN-3 (compound L21) is a quinazoline compound with antifungal activity. CYP51/PD-L1-IN-3 is a dual inhibitor of CYP51 (IC50: 0.205 μM) and PD-L1 (IC50: 0.039 μM), which can induce early apoptosis of fungal cells in the cell cycle. CYP51/PD-L1-IN-3 also significantly reduced intracellular IL-2, NLRP3, and NF-κBp65 protein levels, induced mitochondrial damage and ROS accumulation, and ultimately led to fungal lysis and death .
Cat. No.: HY-116568S
Synonyms: JAU-6476-d4
Cat. No.: HY-P72049
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CYP51A1; P450-14DM; Prev. CYP51; CYPL1; LDM; CYPLI; Lanosterol 14-Alpha Demethylase; CP51; Sterol 14-Alpha Demethylase; Cytochrome P450, Family 51, Subfamily A, Polypeptide 1; Cytochrome P450 51A1; Cytochrome P450, 51 (Lanosterol 14-Alpha-Demethylase); Cy
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
