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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
CaMKIV
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "CaMKIV" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-18271
CAS No.: 1208123-85-6
Target:
Research Areas:
CaMKII-IN-1 is a highly selective inhibitor of CaMKII with an IC50 value of 63nM. It has almost no effect on CaMKIV, MLCK, p38a, Akt1, and PKC.
Cat. No.: HY-134261A
Synonyms: 8-Bromoadenosine-5'-O-diphosphoribose disodium
Target:
Research Areas:
8-Br-ADPR disodium (8-Bromoadenosine-5'-O-diphosphoribose) is a TRPM2 inhibitor and ADPR signaling pathway antagonist. 8-Br-ADPR disodium inhibits glucagon-mediated nuclear calcium signaling and downstream CaMKII/CREB phosphorylation by blocking ADPR-induced TRPM2 activation. 8-Br-ADPR disodium significantly reduces gluconeogenic gene expression and blood glucose levels in diabetic models. 8-Br-ADPR disodium effectively blocks ADPR-mediated calcium signal transduction in NK cells, inhibits immune synapse formation, granzyme B release and cytolytic activity against melanoma cells. 8-Br-ADPR disodium is widely used in studies related to diseases such as diabetes, melanoma and lymphoma .
Cat. No.: HY-134261
CAS No.: 59259-77-7
Synonyms: 8-Bromoadenosine-5'-O-diphosphoribose
Target:
Research Areas:
8-Br-ADPR (8-Bromoadenosine-5'-O-diphosphoribose) is a TRPM2 inhibitor and ADPR signaling pathway antagonist. 8-Br-ADPR inhibits glucagon-mediated nuclear calcium signaling and downstream CaMKII/CREB phosphorylation by blocking ADPR-induced TRPM2 activation. 8-Br-ADPR significantly reduces gluconeogenic gene expression and blood glucose levels in diabetic models. 8-Br-ADPR effectively blocks ADPR-mediated calcium signal transduction in NK cells, inhibits immune synapse formation, granzyme B release and cytolytic activity against melanoma cells. 8-Br-ADPR is widely used in studies related to diseases such as diabetes, melanoma and lymphoma .
Cat. No.: HY-RS01864
Target:
Research Areas:
CAMK4 Human Pre-designed siRNA Set A contains three designed siRNAs for CAMK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17145
Target:
Research Areas:
Camk4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Camk4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P75457
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Calcium/calmodulin-dependent protein kinase type IV;
CaMK IV; CAMK4; CAMK; CAMK-GR
Species:
Source:
Cat. No.: HY-P700579
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CaM kinase-GR; Calspermin
Cat. No.: HY-P85537
Synonyms: Brain Ca; 2; calmodulin dependent protein kinase type 4; Brain Ca; 2; calmodulin dependent protein kinase type IV; Brain Ca -calmodulin dependent protein kinase type IV; Calcium / calmodulin dependent protein kinase type 4 catalytic chain; Calcium / calmodulin dependent protein kinase type IV catalytic chain; Calcium/calmodulin dependent protein kinase IV; Calcium/calmodulin dependent protein kinase type IV; Calcium/calmodulin-dependent protein kinase type IV; CAM kinase 4; CAM kinase GR; CAM kinase IV; CAM kinase-GR; CaMK 4; CAMK GR; CaMK IV; CaMK4; CaMKGR; IV; KCC4_HUMAN; MGC36771.
Cat. No.: HY-P702652
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
