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Isoforms Recommended:	CAMK IV

Results for "

CaMKIV

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CaMK (3) Small Interfering RNA (siRNA) (2) TRP Channel (2)
By Research Areas:	Cancer (2) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18271

CaMKII-IN-1 5 Publications Verification	CaMK	Neurological Disease
CaMKII-IN-1 is a highly selective inhibitor of CaMKII with an IC50 value of 63nM. It has almost no effect on CaMKIV, MLCK, p38a, Akt1, and PKC.

HY-134261A

8-Br-ADPR disodium 8-Bromoadenosine-5'-O-diphosphoribose disodium	CaMK TRP Channel	Metabolic Disease Inflammation/Immunology Cancer
8-Br-ADPR disodium (8-Bromoadenosine-5'-O-diphosphoribose) is a TRPM2 inhibitor and ADPR signaling pathway antagonist. 8-Br-ADPR disodium inhibits glucagon-mediated nuclear calcium signaling and downstream CaMKII/CREB phosphorylation by blocking ADPR-induced TRPM2 activation. 8-Br-ADPR disodium significantly reduces gluconeogenic gene expression and blood glucose levels in diabetic models. 8-Br-ADPR disodium effectively blocks ADPR-mediated calcium signal transduction in NK cells, inhibits immune synapse formation, granzyme B release and cytolytic activity against melanoma cells. 8-Br-ADPR disodium is widely used in studies related to diseases such as diabetes, melanoma and lymphoma .

HY-134261

8-Br-ADPR 8-Bromoadenosine-5'-O-diphosphoribose	TRP Channel CaMK	Metabolic Disease Cancer
8-Br-ADPR (8-Bromoadenosine-5'-O-diphosphoribose) is a TRPM2 inhibitor and ADPR signaling pathway antagonist. 8-Br-ADPR inhibits glucagon-mediated nuclear calcium signaling and downstream CaMKII/CREB phosphorylation by blocking ADPR-induced TRPM2 activation. 8-Br-ADPR significantly reduces gluconeogenic gene expression and blood glucose levels in diabetic models. 8-Br-ADPR effectively blocks ADPR-mediated calcium signal transduction in NK cells, inhibits immune synapse formation, granzyme B release and cytolytic activity against melanoma cells. 8-Br-ADPR is widely used in studies related to diseases such as diabetes, melanoma and lymphoma .

HY-RS01864

CAMK4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CAMK4 Human Pre-designed siRNA Set A contains three designed siRNAs for CAMK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CAMK4 Human Pre-designed siRNA Set A CAMK4 Human Pre-designed siRNA Set A

HY-RS17145

Camk4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Camk4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Camk4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Camk4 Mouse Pre-designed siRNA Set A Camk4 Mouse Pre-designed siRNA Set A

Species:	Human (1) Rat (1) Mouse (1)
Tag:	His (1) Tag Free (1) GST (1)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P75457

	CAMKIV/CAMK4 Protein, Mouse (sf9) Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CAMK4; CAMK; CAMK-GR	Mouse	Sf9 insect cells
	CAMKIV/CAMK4 protein, a calcium/calmodulin-dependent kinase, regulates transcription activators (CREB1, MEF2D, JUN, and RORA) in immune response, inflammation, and memory consolidation. It controls thymocyte selection, TCR signaling, osteoclast and dendritic cell survival, and memory consolidation in hippocampal neurons. It activates MAP kinases, ELK1, ATF2, and potentially participates in spermatogenesis. CAMKIV/CAMK4 Protein, Mouse (sf9) is the recombinant mouse-derived CAMKIV/CAMK4 protein, expressed by Sf9 insect cells, with tag free.

HY-P700579

	CAMKIV/CAMK4 Protein, Rat (His) CaM kinase-GR; Calspermin	Rat	E. coli
	CAMKIV/CAMK4 protein phosphorylates transcriptional activators (CREB1, MEF2D, JUN, RORA) involved in immune response, inflammation, and memory consolidation.CAMKIV/CAMK4 regulate T cell selection, cytokine production, osteoclast/dendritic cell differentiation, and survival.CAMKIV/CAMK4 Protein, Rat (His) is the recombinant rat-derived CAMKIV/CAMK4 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P702652

	CAMKIV/CAMK4 Protein, Human (Active, sf9, GST) CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV	Human	Sf9 insect cells
	CAMKIV/CAMK4 Protein, Human (sf9, GST) is the recombinant human-derived CAMKIV/CAMK4, expressed by Sf9 insect cells , with GST labeled tag.

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Host:	Mouse (3) Rabbit (1)
Reactivity:	Human (4) Rat (1) Mouse (1) Chicken (1) Dog (1) Pig (1)
Application:	IHC-P (1) ICC/IF (1) IP (1) WB (4) FC (1)
Isotype:	IgG (1) IgG2a (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81263A

	CaMKIV Antibody (YA943) CAMK4; CAMK; CAMK-GR; CaMKIV; Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CaM kinase-GR	WB, IHC-P, ICC/IF, IP, FC	Human
	CaMKIV Antibody (YA943) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CaMKIV.

HY-P85421

	CaMKIV Antibody (YA5113) CAMK4; CAMK; CAMK-GR; CaMKIV; Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CaM kinase-GR	WB	Human, Mouse, Rat, Chicken, Dog, Pig
	CaMKIV Antibody (YA5113) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CaMKIV.

HY-P81263

	CaMKIV Antibody (YA942) CAMK4; CAMK; CAMK-GR; CaMKIV; Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CaM kinase-GR	WB	Human
	CaMKIV Antibody (YA942) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CaMKIV.

HY-P85537

	CaMKIV Antibody (YA5229) Brain Ca; 2; calmodulin dependent protein kinase type 4; Brain Ca; 2; calmodulin dependent protein kinase type IV; Brain Ca -calmodulin dependent protein kinase type IV; Calcium / calmodulin dependent protein kinase type 4 catalytic chain; Calcium / calmodulin dependent protein kinase type IV catalytic chain; Calcium/calmodulin dependent protein kinase IV; Calcium/calmodulin dependent protein kinase type IV; Calcium/calmodulin-dependent protein kinase type IV; CAM kinase 4; CAM kinase GR; CAM kinase IV; CAM kinase-GR; CaMK 4; CAMK GR; CaMK IV; CaMK4; CaMKGR; IV; KCC4_HUMAN; MGC36771.	WB	Human
	CaMKIV Antibody (YA5229) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CaMKIV.

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Cat. No.	Product Name		Classification

HY-RS01864

CAMK4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CAMK4 Human Pre-designed siRNA Set A contains three designed siRNAs for CAMK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17145

Camk4 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Camk4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Camk4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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