7 Results for "

CaV2.1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "CaV2.1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1080
CAS No.: 145017-83-0
ω-Agatoxin IVA is a potent, selective P/Q type Ca 2+ (Cav2.1) channel blocker with IC50 values of 2 nM and 90 nM. ω-Agatoxin IVA inhibits glutamate exocytosis and calcium influx elicited by high potassium. ω-Agatoxin IVA inhibits Capsaicin (HY-10448)-induced CGRP release and vasodilation. ω-Agatoxin IVA can be used for the research of neurological and cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-P1080A
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

ω-Agatoxin IVA TFA is a potent, selective P/Q type Ca 2+ (Cav2.1) channel blocker with IC50 values of 2 nM and 90 nM. ω-Agatoxin IVA TFA inhibits glutamate exocytosis and calcium influx elicited by high potassium. ω-Agatoxin IVA TFA inhibits Capsaicin (HY-10448)-induced CGRP release and vasodilation. ω-Agatoxin IVA TFA can be used for the research of neurological and cardiovascular disease .
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Cat. No.: HY-120751
CAS No.: 1309601-26-0
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain .
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Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Calciseptine is a natural polypeptide toxin found in the venom of the black mamba snake (Dendroaspis p. polylepis). Calciseptine is a highly effective and selective blocker of the L-type channel of the Cav1.2 subtype, with an IC50 value of 92 nM. Calciseptine has no effect on Cav3.1, Cav2.2, Cav2.1, Cav1.1, voltage-sensitive sodium channels and potassium channels. Calciseptine exhibits negative inotropic and negative relaxant effects on mice, and does not affect heart rate or the action potential of sinoatrial node pacemaker cells. Calciseptine can be used for research on cardiovascular diseases[1].
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Cat. No.: HY-RS01791
Research Areas:  

Others

CACNA1A Human Pre-designed siRNA Set A contains three designed siRNAs for CACNA1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS21232
Research Areas:  

Others

Cacna1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cacna1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS27749
Research Areas:  

Others

Cacna1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Cacna1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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