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Chebulic acid

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By Targets:	Bacterial (1) Fungal (2) Keap1-Nrf2 (2) Reactive Oxygen Species (ROS) (2) Reference Standards (1)
By Research Areas:	Infection (3) Inflammation/Immunology (1) Metabolic Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N4170

Chebulic acid 2 Publications Verification	Keap1-Nrf2 Reactive Oxygen Species (ROS)	Metabolic Disease
Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

HY-N4170R

Chebulic acid (Standard)	Reference Standards Keap1-Nrf2 Reactive Oxygen Species (ROS)	Metabolic Disease
Chebulic acid (Standard) is the analytical standard of Chebulic acid (HY-N4170). This product is intended for research and analytical applications. Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

HY-N19663

*12-O-Methyl chebulic* acid**	Fungal	Infection Others
12-O-Methyl chebulic acid is an antifungal agent, methylated chebulic acid derivative and probable isolation artifact from Terminalia dhofarica leaves. 12-O-Methyl chebulic acid inhibits growth of several plant pathogens. 12-O-Methyl chebulic acid can be used for the research of phytopathogenic fungal infection and phytopathogenic oomycete infection .

HY-N19081

Terminalia belerica extract	Bacterial	Infection Inflammation/Immunology
Terminalia belerica extract is rich in various bioactive compounds, such as tannins, gallic acid, ellagic acid, chebulic acid, and various sugars including glucose and fructose. Terminalia belerica extract possesses antioxidant, antibacterial, anti-inflammatory, and hepatoprotective effects.

HY-N19784

12,13-Dimethyl chebulate	Fungal	Infection
12,13-Dimethyl chebulate is a methylated chebulic acid derivative that can be found in sugar maple fall leaves and Terminalia dhofarica leaves. 12,13-Dimethyl chebulate exhibits antifungal activity and DPPH scavenging activity. 12,13-Dimethyl chebulate can be used for the research of fungal infection .

Chebulic acid 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Combretaceae Phenols Polyphenols Metabolic Disease Terminalia chebula Retz. Plants Disease Research Fields Source Classification	Keap1-Nrf2 Reactive Oxygen Species (ROS)
Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

Chebulic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Combretaceae Phenols Polyphenols Terminalia chebula Retz. Plants Source Classification	Reference Standards Keap1-Nrf2 Reactive Oxygen Species (ROS)
Chebulic acid (Standard) is the analytical standard of Chebulic acid (HY-N4170). This product is intended for research and analytical applications. Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .

*12-O-Methyl chebulic* acid**	Structural Classification Dipteronia dyeriana Henry Sapindaceae Phenols Polyphenols Plants Source Classification	Fungal
12-O-Methyl chebulic acid is an antifungal agent, methylated chebulic acid derivative and probable isolation artifact from Terminalia dhofarica leaves. 12-O-Methyl chebulic acid inhibits growth of several plant pathogens. 12-O-Methyl chebulic acid can be used for the research of phytopathogenic fungal infection and phytopathogenic oomycete infection .

Terminalia belerica extract	Structural Classification Extract	Bacterial
Terminalia belerica extract is rich in various bioactive compounds, such as tannins, gallic acid, ellagic acid, chebulic acid, and various sugars including glucose and fructose. Terminalia belerica extract possesses antioxidant, antibacterial, anti-inflammatory, and hepatoprotective effects.

12,13-Dimethyl chebulate	Structural Classification Dipteronia dyeriana Henry Ketones, Aldehydes, Acids Sapindaceae Plants Source Classification	Fungal
12,13-Dimethyl chebulate is a methylated chebulic acid derivative that can be found in sugar maple fall leaves and Terminalia dhofarica leaves. 12,13-Dimethyl chebulate exhibits antifungal activity and DPPH scavenging activity. 12,13-Dimethyl chebulate can be used for the research of fungal infection .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Chebulic acid

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