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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
CycY
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "CycY" in MCE Product Catalog:
41
41 Cited Publications
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces cell apoptosis.
Cat. No.: HY-E70665
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CDK17 is highly expressed in terminally differentiated neurons, particularly those found in hippocampal regions and olfactory bulbs. CDK17/CycY Recombinant Human Active Protein Kinase is an ortholog of CDK17 .
Cat. No.: HY-E70667
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CDK18 is a neuronal kinase that phosphorylates TAU protein when overexpressed in human brain. CDK18 shares a conserved PCTAIRE amino acid sequence in the helical α-C region of the kinase N-lobe. CDK18/CycY Recombinant Human Active Protein Kinase is an ortholog of CDK18 .
Cat. No.: HY-P701362
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK15; Serine/Threonine-Protein Kinase PFTAIRE-2; Prev. ALS2CR7; Cell Division Protein Kinase 15; Prev. PFTK2; Cyclin-Dependent Kinase 15; PFTAIRE2; PFTAIRE Protein Kinase 2; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 7 Protein; Ser
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Cat. No.: HY-180355
CAS No.: 2365230-48-2
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SY-5102 is a potent, selective, and orally active cyclin-dependent kinase (CDK7) inhibitor with a Kd value of 0.03 nM. SY-5102 occupies the ATP-binding pocket of CDK7 via non-covalent binding to inhibit CDK7 activity, and downregulates its phosphorylation of cyclin CDK and RNA polymerase II. SY-5102 inhibits cancer cell proliferation, and induces tumor growth inhibition and regression. SY-5102 can be used in research related to triple-negative breast cancer .
Cat. No.: HY-P703047
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CCNY; Cyclin-Y; Prev. C10orf9; Cyc-Y; CBCP1; Chromosome 10 Open Reading Frame 9; CFP1; Cyclin-Box Carrying Protein 1; Cyclin Fold Protein 1; CCNX; Cyclin Box Protein 1; Cyclin Y; Cyclin-X
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Cat. No.: HY-P702925
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK14; PFTAIRE1; Prev. PFTK1; PFTAIRE Protein Kinase 1; Cell Division Protein Kinase 14; HPFTAIRE1; Cyclin-Dependent Kinase 14; KIAA0834; Cyclin Dependent Kinase 14; Serine/Threonine-Protein Kinase PFTAIRE-1; CCNY; Cyclin-Y; Prev. C10orf9; Cyc-Y; CBCP1; C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
