1 Result for "

DPHase

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DPHase" in MCE Product Catalog:

Cat. No.: HY-124178
CAS No.: 24613-06-7
Synonyms: (R)-ICRF 186
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases .
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