(R)-Levrazoxane
(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases.
For research use only. We do not sell to patients.
- CAS No.: 24613-06-7
- Formula: C11H16N4O4
- Molecular Weight:268.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 24613-06-7
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Molecular Weight 268.27
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Formula C11H16N4O4
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SMILES
C[C@H](CN(CC(N1)=O)CC1=O)N(CC(N2)=O)CC2=O
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Synonyms
(R)-ICRF 186
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)