(R)-Levrazoxane
(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases.
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- CAS No.: 24613-06-7
- 화학식: C11H16N4O4
- 분자량:268.27
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 24613-06-7
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분자량 268.27
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화학식 C11H16N4O4
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SMILES
C[C@H](CN(CC(N1)=O)CC1=O)N(CC(N2)=O)CC2=O
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Synonyms
(R)-ICRF 186
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)