Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
ERK2 Substrate
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "ERK2 Substrate" in MCE Product Catalog:
Cat. No.: HY-P5507
CAS No.: 947688-38-2
Synonyms: ERKtide
Cat. No.: HY-P5440
CAS No.: 287721-17-9
Cat. No.: HY-P10421
CAS No.: 915155-20-3
Cat. No.: HY-162460
CAS No.: 3056077-07-4
ERK1/2 inhibitor 10 (Compound 36c) is a potent ERK1 and ERK2 inhibitor (IC50: 0.11 and 0.08 nM respectively). ERK1/2 inhibitor 10 inhibits ERK1/2 and blocks the phosphorylation expression of their downstream substrates p90RSK and c-Myc. ERK1/2 inhibitor 10 induces cell apoptosis and incomplete autophagy-related cell death. ERK1/2 inhibitor 10 shows potent antitumor efficacy against triple-negative breast cancer and colorectal cancer models harboring BRAF and RAS mutations .
Cat. No.: HY-P3992
Target:
Research Areas:
Cat. No.: HY-108959
CAS No.: 800394-83-6
D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
