5-FAM-Dyrktide
5-FAM-Dyrktide is a 5-FAM labeled Dyrktide. Dyrktide, a substrate, is efficiently phosphorylated by DYRK1A (Km=35 μM) but not by ERK2.
For research use only. We do not sell to patients.
- Formula: C100H145N31O23
- Molecular Weight:2149.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CDK6/cyclin D1 reactions monitor the phosphorylation of 3 μM 5-FAM-Dyrktide[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 2149.42
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Formula C100H145N31O23
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Sequence
{5-FAM}-Arg-Arg-Arg-Phe-Arg-Pro-Ala-Ser-Pro-Leu-Arg-Gly-Pro-Pro-Lys
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Sequence Shortening
{5-FAM}-RRRFRPASPLRGPPK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. S Himpel, et al. Specificity determinants of substrate recognition by the protein kinase DYRK1A. J Biol Chem. 2000 Jan 28;275(4):2431-8. [Content Brief]
[2]. Kevin D Freeman-Cook, et al. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J Med Chem. 2021 Jul 8;64(13):9056-9077. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-FAM-Dyrktide Related Classifications
HY-P3992 Related Classifications
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