Fluorescent-labeled Peptides

FITC-labeled α-Bungarotoxin is FITC-conjugated α-Bungarotoxin (HY-P1264). α-Bungarotoxin acts as a competitive antagonist of nicotinic acetylcholine receptors (nAChRs).

Phalloidin-TRITC is a fluorescein derivative of Phalloidin, which can specifically label myof lin and display red fluorescence when labeled and can be observed using Tesred channels.

FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease.

FAM-OVA (257-264) is a biological active peptide. (FAM labeled HY-P1489)

FITC-OVA (323-339) TFA is a biological active peptide. (FITC labeled HY-P0286)

5-FAM-Amylin (human) is a fluorescently labeled peptide derived from human amylin, which is involved in glucose metabolism. 5-FAM-Amylin (human) is an important tool in biochemical research, especially in studies of amyloid fibril formation.

FITC‑Ahx‑Gly‑Arg‑Gly‑Asp‑Ser‑Pro is an FITC-labeled GRGDSP (HY-P0290) peptide bearing an Ahx flexible spacer. FITC fluorescently labeled RGD functional peptide. FITC‑Ahx‑Gly‑Arg‑Gly‑Asp‑Ser‑Pro uses 6‑aminohexanoic acid (Ahx) as a flexible spacer, which reduces the steric hindrance of the fluorescent group and preserves the biological activity of the GRGDSP sequence in recognizing integrin receptors, and is used for fluorescent tracing of integrins or for validation of peptide coupling on hydrogel surfaces.

F-P564 is a FITC (HY-66019)-labeled HIF-1α-derived peptide substrate used to monitor PHD2 prolyl hydroxylase activity. F-P564 undergoes PHD2-mediated hydroxylation of Pro-564 to generate a hydroxyproline-containing peptide, which binds the VBC complex, increasing mass and enhancing fluorescence polarization in the assay. The unhydroxylated form of F-P564 shows no change in fluorescence polarization upon addition of VBC.

Angiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled) is a FAM labeled Angiotensin II human (HY-13948).

Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm). β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). Its active form, β-Amyloid (1-42), may play a key role in the pathogenesis of Alzheimer's disease.

β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).

FITC-β-Amyloid (25-35) is a FITC (HY-66019) labeled β-Amyloid (25-35) (HY-P0128)

(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells.

Semaglutide-FITC (Semaglutide-Lys(FITC)) is a fluorescent tracer probe (Ex/Em = 495/520 nm) obtained by covalently coupling the green fluorescent dye fluorescein isothiocyanate (FITC) (HY-66019) to the long-acting analogue of GLP-1, Semaglutide (HY-114118). Semaglutide-FITC can be used for studies on Semaglutide receptor binding (GLP-1R), cell uptake and endocytosis, in vivo tissue distribution, and the targeting efficiency of delivery systems.

TAT (47-57), FAM-labeled acetate is a 5(6)-Carboxyfluorescein (HY-15940)-labeled TAT (HY-P0281). TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide.

Substance P, FAM-labeled (TFA) is Substance P TFA (HY-P02101A) labeled with FAM fluorophore. Substance P TFA (Neurokinin P TFA) is a neuropeptide that acts as a neurotransmitter and neuromodulator in the central nervous system. The endogenous receptor of Substance P is neurokinin 1 receptor (NK1R).

5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)

Glucagon (1-29), FAM-labeled is a biological active peptide. (FAM labeled HY-P0082)

Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines.

p53 (17-26), FITC labeled is a biological active peptide. p53 (17-26) is a peptide derived from the P53 MDM2 binding domain, with a K_d of 50 nM for MDM2. p53 (17-26) causes cell lysis by damaging cancer cells and nuclear membranes, and induces cancer cell necrosis. p53 (17-26) exhibits antitumor activity and is applicable to research related to pancreatic cancer.