800394-83-6
800394-83-6
Chemical Structure
D-87503
- CAS No.: 800394-83-6
- Formula:C17H15N5OS
- Molecular Weight:337.40
IUPAC Name: 1-allyl-3-(3-(4-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl)thiourea
InChIKey: YKMUCILEPVJXKD-UHFFFAOYSA-N
SMILES: S=C(NCC=C)NC1=CC=C2C(N=C(C3=CC=C(O)C=C3)C=N2)=N1
Biological Activity: D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
D-87503 | D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
