800394-83-6

D-87503 Chemical Structure
800394-83-6

Chemical Structure

D-87503

  • CAS No.: 800394-83-6
  • Formula:C17H15N5OS
  • Molecular Weight:337.40

IUPAC Name: 1-allyl-3-(3-(4-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl)thiourea

InChIKey: YKMUCILEPVJXKD-UHFFFAOYSA-N

SMILES: S=C(NCC=C)NC1=CC=C2C(N=C(C3=CC=C(O)C=C3)C=N2)=N1

Biological Activity: D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway[1].

Cat. No. Product Name Purity Description Pricing
HY-108959 		D-87503 D-87503 is a potent inhibitor of PI3k/Akt/mTOR, with the IC50s of 62 nM and 0.76 μM, respectively for PI3k and Erk2. D-87503 effectively suppressed the target downstream substrates Akt and Rsk1 kinase of the PI3k/Akt/mTOR signaling pathway.
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