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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
FADS2
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "FADS2" in MCE Product Catalog:
6
Research Areas:
Taurolithocholic acid is an orally active bile acid and antiviral agent. Taurolithocholic acid upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis (Ferroptosis), viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis [2] .
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6 Publications Verification
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5 Cited Publications
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SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties .
Cat. No.: HY-RS04667
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FADS2 Human Pre-designed siRNA Set A contains three designed siRNAs for FADS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23340
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Fads2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fads2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-113308S1
CAS No.: 2410279-96-6
Cat. No.: HY-RS16898
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Fads2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fads2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-113308AR
CAS No.: 6042-32-6
Cat. No.: HY-113308AS1
CAS No.: 1265476-97-8
Cat. No.: HY-113308AS2
Cat. No.: HY-113308S
CAS No.: 1265681-64-8
Cat. No.: HY-107410R
CAS No.: 218136-59-5
Research Areas:
SC-26196 (Standard) is the analytical standard of SC-26196 (HY-107410). This product is intended for research and analytical applications. SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties .
Cat. No.: HY-RS11668
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RAPSN Human Pre-designed siRNA Set A contains three designed siRNAs for RAPSN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E71524
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Research Areas:
2-Enoate reductase (EC 1.3.1.31) is an iron sulfoflavin protein (FAD). 2-Enoate reductase (EC 1.3.1.31) acts on various alkyl and aryl αβ-unsaturated carboxylate ions.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
