SC-26196 (Standard)

Cat. No.: HY-107410R: Data Sheet Handling Instructions
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SC-26196 (Standard) is the analytical standard of SC-26196 (HY-107410). This product is intended for research and analytical applications. SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC₅₀=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties.

For research use only. We do not sell to patients.

SC-26196 (Standard) Chemical Structure

CAS No. : 218136-59-5

Size	Stock	Quantity
5 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Description	SC-26196 (Standard) is the analytical standard of SC-26196 (HY-107410). This product is intended for research and analytical applications. SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC₅₀=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties^[1].
IC₅₀ & Target	IC50: 0.2 µM (Delta6 desaturase in a rat liver microsomal assay)^[1]
Molecular Weight	423.55
Formula	C₂₇H₂₉N₅
CAS No.	218136-59-5
SMILES	N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCN(/N=C/C4=CC=CN=C4)CC3
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Obukowicz MG, et al. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66. [Content Brief] [2]. Sibbons CM, et al. Polyunsaturated Fatty Acid Biosynthesis Involving Δ8 Desaturation and Differential DNA Methylation of FADS2 Regulates Proliferation of Human Peripheral Blood Mononuclear Cells. Front Immunol. 2018 Mar 5;9:432. [Content Brief] [3]. Hargrave-Barnes KM, et al. Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase. Obesity (Silver Spring). 2008 Oct;16(10):2245-52. [Content Brief] [4]. Zhang L, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15(2):169-76. [Content Brief]