4 Results for "

FAPα

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "FAPα" in MCE Product Catalog:

Cat. No.: HY-P99902
CAS No.: 1776942-10-9
Synonyms: FAP-IL2v; RO6874281; RG7461

Target:  

Interleukin Related

Research Areas:  

Cancer

Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .
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Cat. No.: HY-177083
CAS No.: 1841402-73-0
Synonyms: AVA-6000
Target:  

FAP

Research Areas:  

Cancer

Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα). Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis) .
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Cat. No.: HY-P10760
CAS No.: 1616592-31-4
Research Areas:  

Cancer

PhAc-ALGP-Dox, a peptide-drug conjugate, is a novel anticancer prodrug, with IC50 values ranged from 311 nM to 34.25 μM for TNBC (E0771), normal murine epithelium (HC-11), human TNBC (MDA-MB-231 and MDA-MB-468), human CrC (LS 174T), normal human epithelium (HME-1) cells .
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Cat. No.: HY-P11823
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology Cancer

FAPα/DPP4 fluorogenic substrate-1 is a fluorogenic macrocyclic peptide substrate that can be cleaved by FAPα and DPP4. FAPα/DPP4 fluorogenic substrate-1 can be used in the research of cancer and type 2 diabetes .
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