PhAc-ALGP-Dox
PhAc-ALGP-Dox, a peptide-drug conjugate, is a novel anticancer prodrug, with IC50 values ranged from 311 nM to 34.25 μM for TNBC (E0771), normal murine epithelium (HC-11), human TNBC (MDA-MB-231 and MDA-MB-468), human CrC (LS 174T), normal human epithelium (HME-1) cells.
For research use only. We do not sell to patients.
- CAS No.: 1616592-31-4
- Formula: C45H58N5O19P
- Molecular Weight:1003.94
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
PhAc-ALGP-Dox is sequentially activated via a tumor-specific two-step cleavage, initiated by extracellular THOP1 and further processed by FAPα/DPP4[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1616592-31-4
-
Molecular Weight 1003.94
-
Formula C45H58N5O19P
-
Sequence
{Phosphonoacetyl}-Ala-Leu-Gly-Pro-{Dox}
-
Sequence Shortening
{Phosphonoacetyl}-ALGP-{Dox}
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PhAc-ALGP-Dox Related Classifications
HY-P10760 Related Classifications
Powered by Bioz