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Cat. No.: HY-P11823

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FAPα/DPP4 flurogenic substrate-1

FAPα/DPP4 fluorogenic substrate-1 is a fluorogenic macrocyclic peptide substrate that can be cleaved by FAPα and DPP4. FAPα/DPP4 fluorogenic substrate-1 can be used in the research of cancer and type 2 diabetes.

For research use only. We do not sell to patients.

Formula: C₆₃H₈₁N₁₇O₂₁S₂
Molecular Weight:1476.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

FAPα/DPP4 flurogenic substrate-1 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 1476.55
Formula C₆₃H₈₁N₁₇O₂₁S₂
Sequence

Chain1:Cys-Val-{S-Gly(OH)}-Phe-Gln-Asn-Ala-Asp-Cys-Gly;Chain2:{2-(7-amino-2-oxo-2H-chromen-4-yl)acetamide}-Pro-{Gly(amino)}-{bis(but-1-yne)} (Carba sulfide bridge:Chain 1 Cys1-Chain 2 {bis(but-1-yne)};Chain 1 Cys9-Chain 2 {bis(but-1-yne)} )
Sequence Shortening

Chain1:CV-{S-Gly(OH)}-FQNADCG;Chain2:{2-(7-amino-2-oxo-2H-chromen-4-yl)acetamide}-P-{Gly(amino)}-{bis(but-1-yne)} (Carba sulfide bridge:Chain 1 Cys1-Chain 2 {bis(but-1-yne)};Chain 1 Cys9-Chain 2 {bis(but-1-yne)} )
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Faucher FF, et al.. Macrocyclic Phage Display for Identification of Selective Protease Substrates. Journal of the American Chemical Society. 2025 Jul 30;147(30):26307-26318. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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