2 Results for "

FE200665

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "FE200665" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P3609
CAS No.: 228546-92-7
Synonyms: JNJ 38488502; FE 200665
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain .
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Cat. No.: HY-111011
CAS No.: 958873-83-1
Synonyms: JNJ 38488502 acetate; FE 200665 acetate
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

CR 665 (JNJ 38488502) acetate is a kappa-opioid agonist that may effectively treat visceral pain by activating receptors on afferent nerves within the gut. CR 665 acetate exhibits peripheral selectivity, differentiating its pharmacokinetic profile from that of non-selective opioids like oxycodone. CR 665 acetate has demonstrated a beneficial effect on visceral pain tolerance thresholds without the delayed analgesic response characteristic of opioids that penetrate the brain. CR 665 acetate is proposed for use in managing postoperative pain due to its pain-relieving properties.
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