7 Results for "

FGFR2b

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "FGFR2b" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P99010
CAS No.: 1952272-74-0
Synonyms: AMG-552; FPA-144

Target:  

FGFR

Research Areas:  

Cancer

Bemarituzumab is a humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has antitumor activity against gastric and breast cancer [2].
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Cat. No.: HY-P99010A

Research Areas:  

Cancer

Bemarituzumab (FUT8-KO) is an anti-FGFR2b monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Bemarituzumab (FUT8-KO) lacks a core fucose in the polysaccharide portion of the Fc domain of the antibody, and results in a high affinity to human FcγRIIIa .
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Cat. No.: HY-178238
CAS No.: 3040077-52-6
Research Areas:  

Cancer

LD2-3 is a cytotoxic compound derived from Exatecan (HY-13631), designed to be conjugated with anti-FGFR2b or anti-CEA antibodies to form intact antibody-drug conjugate (ADC) molecules. LD2-3 exhibits a remarkable bystander killing effect: it not only effectively kills FGFR2b-positive tumor cells, but also eliminates surrounding FGFR2b-negative cells in co-culture and mixed tumor xenograft models, thereby inducing complete tumor regression. LD2-3 can be used for anti-tumor research in relevant fields such as gastric cancer and lung cancer [2].
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Cat. No.: HY-176927
CAS No.: 3031725-06-8
Research Areas:  

Cancer

ADC-VI (Compound 6) is a conjugate of a toxic molecule and a linker, in which the cytotoxin carried by CPD6 is Deruxtecan (HY-13631E). Tricyclene is used to form an antibody-drug conjugate (ADC) by a chemical conjugation reaction through linking with an anti-FGFR2b antibody .
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Cat. No.: HY-P72645
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BEK, FGFR2IIIc; CD332; FGF R2b; FGFR2 beta; FGFR2; FGFR2b;  Fibroblast growth factor receptor 2 (IIIc)
Species:  
Source:  
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Cat. No.: HY-P72646
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BFR-1; FGFR2IIIb; KGFR; CD332; FGF R2b; FGFR2 beta; FGFR2; FGFR2b;  Fibroblast growth factor receptor 2 (IIIb)
Species:  
Source:  
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Cat. No.: HY-RS04916
Research Areas:  

Others

Fgfr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fgfr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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