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Bemarituzumab (FUT8-KO)

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Based on 1 Customer Validation

Bemarituzumab (FUT8-KO) is an anti-FGFR2b monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Bemarituzumab (FUT8-KO) lacks a core fucose in the polysaccharide portion of the Fc domain of the antibody, and results in a high affinity to human FcγRIIIa.

For research use only. We do not sell to patients.

  • Purity: 99%
  • Molecular Weight:143.86 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bemarituzumab (FUT8-KO)
  • Experimental Validation Results for Bemarituzumab (FUT8-KO)
  • Experimental Validation Results for Bemarituzumab (FUT8-KO)
  • Bemarituzumab (FUT8-KO) Chemical Structure
    Bemarituzumab (FUT8-KO) Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of Bemarituzumab (FUT8-KO):

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized hu-FGFR2-β-IIIb-ECD-His can bind Bemarituzumab (FUT8-KO). The EC50 for this effect is 19.97 ng/mL.

  • 1/16

    Loaded Bemarituzumab (FUT8-KO) on AHC2 biosensor, can bind FGFR-2 beta (IIIb) Protein, Human (HEK293, His, HY-P72646) with an affinity constant of 2.530E-09 M as determined in BLI assay.

  • Bemarituzumab (FUT8-KO) Chemical Structure
    1/16
  • Bemarituzumab (FUT8-KO)
  • Immobilized hu-FGFR2-β-IIIb-ECD-His can bind Bemarituzumab (FUT8-KO). The EC50 for this effect is 19.97 ng/mL.
  • Loaded Bemarituzumab (FUT8-KO) on AHC2 biosensor, can bind FGFR-2 beta (IIIb) Protein, Human (HEK293, His, HY-P72646) with an affinity constant of 2.530E-09 M as determined in BLI assay.
  • IgG1-kappa