3031725-06-8
Chemical Structure
ADC-VI
- CAS No.: 3031725-06-8
- Formula:C63H77FN8O22
- Molecular Weight:1317.32
SMILES: COCCOCCOCCOCCOC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)NC([C@H](C)NC([C@H](C(C)C)NC(CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(NCCN9C(C=CC9=O)=O)=O)=O)=O)=O
Biological Activity: ADC-VI (Compound 6) is a conjugate of a toxic molecule and a linker, in which the cytotoxin carried by CPD6 is Deruxtecan (HY-13631E). Tricyclene is used to form an antibody-drug conjugate (ADC) by a chemical conjugation reaction through linking with an anti-FGFR2b antibody[1].
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ADC-VI | ADC-VI (Compound 6) is a conjugate of a toxic molecule and a linker, in which the cytotoxin carried by CPD6 is Deruxtecan (HY-13631E). Tricyclene is used to form an antibody-drug conjugate (ADC) by a chemical conjugation reaction through linking with an anti-FGFR2b antibody. | |||||||||||||||||||||
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Keywords