19 Results for "

Factor+H

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Factor+H" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
Cat. No.: HY-P991067
CAS No.: 2724922-85-2
Synonyms: KP-104

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) . .
Cat. No.: HY-P2969
CAS No.: 80295-66-5
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .
Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Research Areas:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) is a bifunctional fusion protein composed of a humanized anti-C3d monoclonal antibody linked to the first five common repeat (fH1-5) domains of two complement factors H. Ebribafusp alfa is a tissue-targeted complement inhibitor designed to inhibit complement activity at the lesion site while minimizing systemic complement blockade. Ebribafusp alfa can be used for research on kidney diseases, lupus nephritis, and complement component 3 glomerulonephropathy . The recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
Cat. No.: HY-P74232
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement factor H; Protein beta-1-H; CFH
Species:  
Source:  
Cat. No.: HY-P72946
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement factor H; H factor 1; CFH; HF; HF1; HF2
Species:  
Source:  
Cat. No.: HY-P72946Y
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement factor H; H factor 1; CFH; HF; HF1; HF2
Species:  
Source:  
Cat. No.: HY-P83616
Synonyms: AHUS1; AMBP1; ARMD4; ARMS1; beta1H; CFH; CFHL3; complement factor H; isoform b; Factor H; factor H like 1; FHL1; HF1; HF2; HUS

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

Cat. No.: HY-P7890A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuComplement factor H/CFH, His; Complement factor H; CFH
Species:  
Source:  
Cat. No.: HY-P7890
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuComplement factor H/CFH, His; Complement factor H; CFH
Species:  
Source:  
Cat. No.: HY-P7830
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuComplement factor H/CFH, His; Complement factor H; Protein beta-1-H; CFH
Species:  
Source:  
Cat. No.: HY-P70102
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuComplement factor H-related protein 5/CFHR5, His; Complement factor H-related protein 5; CFHR5; CFHL5; FHR5
Species:  
Source:  
Cat. No.: HY-P72690
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement factor H-related protein 4; FHR-4; CFHR4; CFHL4
Species:  
Source:  
Cat. No.: HY-P70031
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuComplement factor H-related protein 2/CFHR2, His; Complement Factor H-Related Protein 2; FHR-2; DDESK59; H Factor-Like 3; H Factor-Like Protein 2; CFHR2; CFHL2; FHR2; HFL3
Species:  
Source:  
Cat. No.: HY-P72691
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Complement factor H-related protein 3; FHR-3; DOWN16; CFHR3; CFHL3
Species:  
Source:  
Cat. No.: HY-P991954

Target:  

Complement System Syk

Research Areas:  

Inflammation/Immunology Cancer

GT103 is a human-derived monoclonal antibody targeting complement factor H (CFH). GT103 binds to a conformationally distinct epitope of CFH on tumor cells. GT103 activates the classical complement pathway, induces complement-dependent cytotoxicity, and triggers antibody-dependent cellular phagocytosis (ADCP) of tumor cells. GT103 increases calreticulin translocation to tumor cell plasma membranes. GT103 mediates B-cell activation via Syk kinase phosphorylation. GT103 inhibits tumor growth and metastasis in animal models. GT103 can be used for the research of non-small cell lung cancer .
Cat. No.: HY-P70055
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuComplement Factor H-related 1/CFHR1, His; Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2
Species:  
Source:  
Cat. No.: HY-P810959
Synonyms: KIAA0651, LFP40, ARHGEF2, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, GEF-H1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

Cat. No.: HY-P811178
Synonyms: KIAA0651; LFP40; Rho guanine nucleotide exchange factor 2; Guanine nucleotide exchange factor H1; GEF-H1; Microtubule-regulated Rho-GEF; Proliferating cell nucleolar antigen p40

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse

Cat. No.: HY-P811176
Synonyms: KIAA0651, LFP40, ARHGEF2, Rho guanine nucleotide exchange factor 2, Guanine nucleotide exchange factor H1, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, GEF-H1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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