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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
GDC0927
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "GDC0927" in MCE Product Catalog:
3
Target:
Research Areas:
GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist .
Cat. No.: HY-111484A
CAS No.: 1443983-36-5
Synonyms: SRN-927 Racemate
Target:
Research Areas:
GDC-0927 Racemate (SRN-927 Racemate) is an estrogen receptor (ER) degrader that can effectively inhibit the activity of ER-α with an IC50 value of 0.2 nM and can be used in diseases related to estrogen receptors.
Cat. No.: HY-111484R
CAS No.: 1642297-01-5
Synonyms: SRN-927 (Standard)
Research Areas:
GDC-0927 (Standard) is the analytical standard of GDC-0927 (HY-111484). This product is intended for research and analytical applications. GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist .
Synonyms: (R)-SRN-927
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Research Areas:
(R)-GDC-0927 ((R)-SRN-927) is a (R)-enantiomer of GDC-0927 (HY-111484) .
Cat. No.: HY-141551B
Target:
Research Areas:
(R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader) .
Target:
Research Areas:
GNE-274 is a structural analog of the ER degrader GDC-0927 and is a non-degrader. GNE-274 does not induce conversion of ER in breast cancer cell lines and functions as a partial ER agonist (partial ER agonist). GNE-274 increases the chromatin accessibility of ER-DNA binding sites, whereas GDC-0927 does not. GNE-274 is an effective ER ligand binding domain (LBD) inhibitor. GNE-274 can be used in cancer research.
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Protocols
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