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Cat. No.: HY-111484R

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GDC-0927 (Standard)

Name: GDC-0927 (Standard)
Brand: MedChemExpress
SKU: HY-111484R
Availability: PreOrder

(Synonyms: SRN-927 (Standard))

GDC-0927 (Standard) is the analytical standard of GDC-0927 (HY-111484). This product is intended for research and analytical applications. GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist.

For research use only. We do not sell to patients.

CAS No.: 1642297-01-5
Formula: C₂₈H₂₈FNO₄
Molecular Weight:461.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GDC-0927 (Standard) Chemical Structure

CAS No.: 1642297-01-5

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1642297-01-5
Molecular Weight 461.52
Formula C₂₈H₂₈FNO₄
SMILES

OC1=CC=C2C(C(C)=C(C3=CC=CC(O)=C3)[C@H](C4=CC=C(OCCN5CC(CF)C5)C=C4)O2)=C1
Synonyms

SRN-927 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. MN Dickler, et al. Abstract PD5-10: A first-in-human phase I study to evaluate the oral selective estrogen receptor degrader (SERD), GDC-0927, in postmenopausal women with estrogen receptor positive (ER+) HER2-negative metastatic breast cancer (BC). AACR; Cancer Res 2018;78(4 Suppl):Abstract nr PD5-10.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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