1. Others
  2. Estrogen Receptor/ERR

GDC-0927 Racemate (Synonyms: SRN-927 Racemate)

Cat. No.: HY-111484A
Handling Instructions

GDC-0927 Racemate is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.

For research use only. We do not sell to patients.

GDC-0927 Racemate Chemical Structure

GDC-0927 Racemate Chemical Structure

CAS No. : 1443983-36-5

Size Price Stock
5 mg USD 600 Get quote
10 mg USD 900 Get quote
25 mg USD 1950 Get quote
50 mg USD 3100 Get quote

* Please select Quantity before adding items.

Other Forms of GDC-0927 Racemate:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

GDC-0927 Racemate is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.

IC50 & Target

IC50: 0.2 nM (ER-α)[1]

In Vitro

GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1668 mL 10.8338 mL 21.6675 mL
5 mM 0.4334 mL 2.1668 mL 4.3335 mL
10 mM 0.2167 mL 1.0834 mL 2.1668 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

461.52

Formula

C₂₈H₂₈FNO₄

CAS No.

1443983-36-5

SMILES

OC1=CC=C2C(C(C)=C(C3=CC=CC(O)=C3)C(C4=CC=C(OCCN5CC(CF)C5)C=C4)O2)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
GDC-0927 Racemate
Cat. No.:
HY-111484A
Quantity:

GDC-0927 Racemate

Cat. No.: HY-111484A