1 Result for "

GPI1046

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GPI1046" in MCE Product Catalog:

Cat. No.: HY-124619
CAS No.: 186452-09-5
Purity:  99.79%
Target:  

EAAT HIV

Research Areas:  

Neurological Disease

GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity .
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