4 Results for "

GnIH

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "GnIH" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1428
CAS No.: 311309-25-8
Research Areas:  

Endocrinology

RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1, respectively .
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Cat. No.: HY-P1250
CAS No.: 311309-27-0
Synonyms: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human)
Research Areas:  

Neurological Disease

RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM .
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Cat. No.: HY-P10780
Synonyms: Neuropeptide NPVF (mouse)
RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3β-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development .
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Cat. No.: HY-P1250A
Synonyms: Neuropeptide VF(124-131)(human) TFA; Neuropeptide NPVF (human) TFA
Research Areas:  

Neurological Disease

RFRP-3 (Neuropeptide VF(124-131))(human) TFA, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM .
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