311309-27-0
Chemical Structure
RFRP-3(human)
Synonym(s): Neuropeptide VF(124-131)(human);Neuropeptide NPVF (human)
- CAS No.: 311309-27-0
- Formula:C45H72N14O10
- Molecular Weight:969.14
IUPAC Name: (S)-2-((S)-1-(L-valyl-L-prolyl-L-asparaginyl-L-leucyl)pyrrolidine-2-carboxamido)-N1-((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)pentanediamide
InChIKey: JFZCLMZUABKABL-GVCDGELBSA-N
SMILES: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H]2N(C([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H]3N(C([C@H](C(C)C)N)=O)CCC3)=O)=O)=O)CCC2)=O)=O)=O
Biological Activity: RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM[1].
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RFRP-3(human) | 99.43% | RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 nM. | ||||||||||||||||||||
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Keywords
