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Results for "

GyK

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2917
    Glycerol kinase, microorganism

    GyK

    		 Nuclear Hormone Receptor 4A/NR4A Metabolic Disease Inflammation/Immunology
    Glycerol kinase, microorganism (GyK) acts as a NR4A1 inhibitor with enzymatic activity. It directly binds to and inhibits the transcription factor NR4A1, thereby negatively regulating hepatic gluconeogenesis and reducing blood glucose levels. Glycerol kinase, microorganism positively regulates UCP1 expression via partial dependence on the β-adrenergic receptor-cAMP-CREB pathway, promotes browning of white adipose tissue and thermogenesis, and further modulates intracellular fatty acid composition and energy metabolism. In diabetic mouse models, overexpression of Glycerol kinase effectively antagonizes NR4A1-induced hyperglycemia, demonstrating potential for improving glucose homeostasis. Glycerol kinase, microorganism can be used for studies on diabetes and obesity .
    Glycerol kinase, microorganism
  • HY-P2917B
    Glycerol kinase, Flavobacterium meningosepticum

    GyK, Flavobacterium meningosepticum

    		 Endogenous Metabolite Metabolic Disease
    Glycerol kinase, Flavobacterium meningosepticum (GyK, Flavobacterium meningosepticum) is a thermostable glycerol kinase isolated from Flavobacterium meningosepticum. Glycerol kinase, Flavobacterium meningosepticum catalyzes the first step in glycerol metabolism by converting triol to glycerol-3-p (G3P). Glycerol kinase, Flavobacterium meningosepticum is essential for regulating glycerol uptake in cells that is independent of channels or facilitators and is useful for biochemical studies .
    Glycerol kinase, Flavobacterium meningosepticum
  • HY-P2917A
    Glycerol kinase, Cellulomonas sp.

    GyK, Cellulomonas sp.

    		 Endogenous Metabolite Others
    Glycerol kinase, Cellulomonas sp. (EC 2.7.1.30) is a bacterial sugar kinase, is often used in biochemical studies. Glycerol kinase, Cellulomonas sp. catalyzes the first step of glycerol metabolism by transforming the triol into glycerol-3-P (G3P). Glycerol kinase, Cellulomonas sp. is crucial for regulating channel/facilitator-independent uptake of glycerol into the cell .
    Glycerol kinase, Cellulomonas sp.
  • HY-P10012
    Pendetide

    GyK-DTPA

    		 Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs) Cancer
    Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma . Pendetide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
    Pendetide
  • HY-RS17180
    Gk Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Gk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gk Mouse Pre-designed siRNA Set A
    Gk Mouse Pre-designed siRNA Set A
  • HY-RS23631
    Gk Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Gk Rat Pre-designed siRNA Set A contains three designed siRNAs for Gk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Gk Rat Pre-designed siRNA Set A
    Gk Rat Pre-designed siRNA Set A

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