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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
HEC-1A cells
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "HEC-1A cells" in MCE Product Catalog:
Target:
Research Areas:
TSI-01 is a selective LPCAT2 inhibitor, with IC50 values of 0.47 μM and 3.02 μM against LPCAT2 and LPCAT1, respectively. TSI-01 competitively inhibits acetyl-CoA (acetyl-CoA) targeting the lysophosphatidic acid acetyltransferase activity of LPCAT2, and suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. TSI-01 inhibits the proliferation of endometrial cancer cells and promotes endometrial cancer cell apoptosis (apoptosis). TSI-01 can be used for the research of endometrial cancer and PAF-related inflammatory diseases .
Cat. No.: HY-N2852
CAS No.: 13059-93-3
Target:
Cat. No.: HY-160962
CAS No.: 1331880-08-0
SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC50 < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model .
Cat. No.: HY-159495
Target:
Research Areas:
Keap1-Nrf2-IN-21 (compound 4d) is a glucose metabolism inhibitor with antitumor activity. Keap1-Nrf2-IN-21 inhibits glycolytic activity of cancer cells by targeting the glycolytic pathway, especially by affecting the Keap1-Nrf2 signaling pathway, thereby inhibiting tumor growth. Keap1-Nrf2-IN-21 exhibits cytotoxicity against the HEC1A cell line (IC50=2.60 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
