1331880-08-0
1331880-08-0
Chemical Structure
SM1044
- CAS No.: 1331880-08-0
- Formula:C34H55NO10
- Molecular Weight:637.80
InChIKey: CYJOFOZKQKUVJA-CHLIXCKASA-N
SMILES: C[C@@H]1[C@@]2([H])[C@]34[C@](O[C@](OO3)(CC[C@@]4([H])[C@@H](CC2)C)C)([H])O[C@@H]1OCCNCCO[C@@H]5[C@@H]([C@@]6([H])[C@]78[C@](O[C@](OO7)(CC[C@@]8([H])[C@@H](CC6)C)C)([H])O5)C
Biological Activity: SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC50 < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model[1].
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SM1044 | SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC50 < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model. | |||||||||||||||||||||
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