3 Results for "

HOG cells

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "HOG cells" in MCE Product Catalog:

Cat. No.: HY-10823
CAS No.: 139987-54-5
Synonyms: GW1843; 1843U89; OSI-7904
Research Areas:  

Cancer

OSI-7904L (GW1843; 1843U89; OSI-7904) is a thymidylate synthase (TS) inhibitor with a Ki of 90 pM. OSI-7904L blocks de novo synthesis of thymidine nucleotides, DNA synthesis and induces cell death. OSI-7904L inhibits the growth of human cells, induces tumor regression, and achieves durable antitumor effects in mouse xenograft models. OSI-7904L can be used in research related to colon adenocarcinoma .
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Cat. No.: HY-181640
CAS No.: 244289-53-0
Target:  

HDAC Apoptosis

Research Areas:  

Neurological Disease Cancer

HDAC1/3-IN-1 is a selective HDAC1/3 inhibitor, with IC50 values of 256 nM and 340.3 nM against HDAC1 and HDAC3, respectively. HDAC1/3-IN-1 increases the SubG1 cell population and promotes apoptosis of glioma cells and glioblastoma stem cells. HDAC1/3-IN-1 can be used in studies related to glioblastoma .
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Cat. No.: HY-181683
Research Areas:  

Metabolic Disease

Antidiabetic agent 8 is an orally active multi-target inhibitor, with IC50 values of 9.79, 6.36 and 19.08 μM against α-glucosidase, α-amylase and PTP1B, respectively. Antidiabetic agent 8 reduces postprandial blood glucose elevation. Antidiabetic agent 8 can be used in the research of type 2 diabetes .
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