1 Result for "

HRGYR

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HRGYR" in MCE Product Catalog:

Cat. No.: HY-P5272
CAS No.: 112844-49-2
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
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